Ajay is BHF Chair of Cardiology and Executive Dean of the Faculty of Life Sciences & Medicine at King's College London, and an Honorary Consultant Cardiologist at King’s College Hospital.
Ajay has a long-standing track record of innovative research in the pathophysiology of heart failure, both in experimental models and patients. He has published seminal work on the roles of redox signalling, nitric oxide and NADPH oxidase proteins in heart failure. His clinical expertise includes interventional cardiology and heart failure.
The current experimental focus of his lab is on altered intermediary metabolism as a driver of heart failure, employing integrative approaches including in vivo gene-modified models, stable isotope-resolved metabolomics and human iPSC-derived cardiomyocytes and engineered heart tissue. His clinical work includes first-in-human experimental medicine studies in the cardiac catheterisation laboratory, clinical informatics & AI, and clinical trials.