Dr Filipa Simões, Co-director of the Oxford Organoid Hub, appears on The Stem Cell Podcast to discuss how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury.
Filipa talks about her work using zebrafish models, stem cell-derived cardiac organoids, and spatial genomics approaches to explore the molecular signals that govern macrophage identity and function, with the goal of uncovering new strategies to promote cardiac regeneration and limit fibrosis.
