Douglas L. Mann, MD is Ada L. Steininger Professor in Cardiology and Professor of Cell Biology and Physiology at Washington University in St. Louis School of Medicine.
Douglas’s primary research interest has been the molecular and cellular basis of heart failure, with particular emphasis on the role of innate immunity in heart failure. His laboratory has focused on the basic mechanisms that contribute to left ventricular remodeling and reverse left ventricular remodeling. He has been engaged in translational research for over two decades, and has also sought to translate concepts derived in his laboratory into phase I, II, III and IV clinical trials.
Douglas has served as Chair of REACT's Independent Strategic Advisory Board since 2026.