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MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies
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  • Back Our research
    • Back Our research strategy We are connecting scientists and clinicians, working together to tackle three key research challenges.
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    • Back Heart icon Target discovery We are identifying, prioritising and validating therapeutic nucleic acids that will leverage endogenous reparative processes to generate new heart muscle, promote vessel formation and resolve fibrosis.
    • Back Heart icon Cardiac delivery We are developing cardiac-specific targeting mechanisms to administer therapeutic nucleic acids to the heart using innovative nanoformulations and viral vectors.
    • Back Heart icon Clinical translation We are building a pipeline to test and evaluate new medicines based on therapeutic nucleic acids and readying ourselves for a structured approach to clinical trials.
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    • Back Our approach to research We are building a community and environment that fosters open, collaborative and equitable research practice.
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    • Back Photo of Paul Riley. Read: Paul Riley elected as Fellow of the Royal Society 27 May 2026
    • Back Computer-generated image of RNA molecule. Read: Independent Strategic Advisory Board meets 20 April 2026
    • Back People sat in auditorium. Read: first symposium brings REACT together 25 March 2026
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Heart icon on gradient background. 9 June 2026 Podcast The Stem Cell Podcast: Healing hearts with macrophages
Photo of Paul Riley. 27 May 2026 News Paul Riley elected as Fellow of the Royal Society
Computer-generated image of RNA molecule. 20 April 2026 News REACT Independent Strategic Advisory Board meets for the first time
People sat in auditorium. 25 March 2026 News First annual symposium brings together growing REACT community
The Naked Scientists logo overlaid on photo of anatomical human heart model on table. 17 February 2026 Podcast The Naked Scientists: Heart failure - can you mend a broken heart?
Andy Baker in suit and tie holding medal. 20 November 2025 News Andy Baker awarded the RSE Sir James Black Medal
British Heart Foundation Screenshot of participants in online webinar. 10 November 2025 Film BHF Heart Matters Live: Heart failure – how do I live well with this condition?

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MRC/BHF CoRE in Advanced Cardiac Therapies Regenerating injured hearts and reversing established damage with genetic medicines.

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