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MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies
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    • Back Our research We are connecting scientists and clinicians, working together to tackle three key research challenges.
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    • Back Heart icon Target discovery We are identifying, prioritising and validating therapeutic nucleic acids that will leverage endogenous reparative processes to generate new heart muscle, promote vessel formation and resolve fibrosis.
    • Back Heart icon Cardiac delivery We are developing cardiac-specific targeting mechanisms to administer therapeutic nucleic acids to the heart using innovative nanoformulations and viral vectors.
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    • Back Screenshot of opening sequence of film, reading Gene Horizons. Watch: Gene Horizons film released by EuroGCT 3 October 2025
    • Back Screenshot of participants in online webinar. Watch: Paul Riley joins BHF Heart Matters Live 10 November 2025
    • Back Andy Baker in suit and tie holding medal. News: Andy Baker receives RSE medal 20 November 2025
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Andy Baker in suit and tie holding medal. 20 November 2025 News Andy Baker awarded the RSE Sir James Black Medal
British Heart Foundation Screenshot of participants in online webinar. 10 November 2025 Film BHF Heart Matters Live: Heart failure – how do I live well with this condition?
Trusted content Background gradient image. 7 November 2025 Academic publication The Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies …
Trusted content Gradient background. 20 October 2025 Academic publication Ribonucleic acid and gene therapies in cardiovascular disease: clinical applications, delivery challenges and emerging…
EuroGCT Screenshot of opening sequence of film, reading Gene Horizons. 3 October 2025 Film Gene Horizons
Trusted content Gradient background. 22 September 2025 Academic publication Proregenerative MicroRNAs to Repair the Damaged Heart
Trusted content Gradient background. 16 September 2025 Academic publication Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis
Trusted content Gradient background. 10 September 2025 Academic publication Small Interfering RNA Therapy Targeting the Long Noncoding RNA SMILR for Therapeutic Intervention in Coronary Artery…
Trusted content Background gradient image. 25 August 2025 Academic publication Gene therapy in cardiac and vascular diseases: a review of approaches to treat genetic and common cardiovascular…
Trusted content Gradient background. 7 March 2025 Academic publication Genetic tracing and topography of spontaneous and stimulated cardiac regeneration in mice

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MRC/BHF CoRE in Advanced Cardiac Therapies Regenerating injured hearts and reversing established damage with genetic medicines.

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