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MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies
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  • Back Our research
    • Back Our research We are connecting scientists and clinicians, working together to tackle three key research challenges.
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    • Back Heart icon Target discovery We are identifying, prioritising and validating therapeutic nucleic acids that will leverage endogenous reparative processes to generate new heart muscle, promote vessel formation and resolve fibrosis.
    • Back Heart icon Cardiac delivery We are developing cardiac-specific targeting mechanisms to administer therapeutic nucleic acids to the heart using innovative nanoformulations and viral vectors.
    • Back Heart icon Clinical translation We are building a pipeline to test and evaluate new medicines based on therapeutic nucleic acids and readying ourselves for a structured approach to clinical trials.
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    • Back Our approach We are building a community and environment that fosters open, collaborative and equitable research practice.
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    • Back Speaker at front of room talking to gathered group of people. Patient partnerships
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    • Back Opportunities Discover what our centre offers staff, students, collaborators and partners, and how you can get involved.
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    • Back Screenshot of opening sequence of film, reading Gene Horizons. Watch: Gene Horizons film released by EuroGCT 3 October 2025
    • Back Screenshot of participants in online webinar. Watch: Paul Riley joins BHF Heart Matters Live 10 November 2025
    • Back Andy Baker in suit and tie holding medal. News: Andy Baker receives RSE medal 20 November 2025
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Leadership team

The REACT leadership team are responsible for all decisions related to the MRC/BHF CoRE in Advanced Cardiac Therapies.

The leadership team is chaired by Professor Mauro Giacca, REACT Director, with support from Co-Directors Professor Andy Baker and Professor Paul Riley.

Further members of the team bring expertise in areas including translation, clinical practice, dissemination and training, research culture and operations.

Our leadership team

Portrait photo of Andy Baker. Professor Andy Baker Co-director University of Edinburgh
Portrait photo of Jacqueline Barry. Dr Jacqueline Barry Translational Development Lead Cell and Gene Therapy Catapult
Portrait photo of Clare Blackburn. Professor Clare Blackburn Dissemination and Training Lead University of Edinburgh
Portrait photo of Robin Choudhury. Professor Robin Choudhury Clinical Lead University of Oxford
Portrait photo of Mauro Giacca. Professor Mauro Giacca Director King's College London
Portrait photo of Nicola Haines. Dr Nicola Haines Chief Operating Officer King's College London
Portrait photo of David Newby. Professor David Newby Clinical Lead University of Edinburgh
Portrait photo of Paul Riley. Professor Paul Riley Co-director University of Oxford
Portrait photo of Ajay Shah. Professor Ajay Shah Clinical Lead King's College London
Portrait photo of Emily Williams. Professor Emily Williams Research Culture and EDI Lead King's College London
MRC/BHF CoRE in Advanced Cardiac Therapies Regenerating injured hearts and reversing established damage with genetic medicines.

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