Determining mechanisms of cardiomyocyte proliferation-driven vascularisation
Although survival rates after myocardial infarction (MI) have improved, permanent loss of heart muscle cells often results in progressive heart failure. Restoring blood supply through angiogenesis (the growth of new blood vessels) could protect vulnerable …
Identifying early response RNA binding proteins in cardiac fibrosis
Giancarlo Forte …
Computationally identifying conserved drivers of cardiac repair
The injured heart undergoes coordinated phases of inflammation, proliferation and maturation, comprising interconnected biological processes that determine reparative capacity. These include regeneration of lost myocardium, recruitment and activation of …
Exploring long non-coding RNAs as therapeutic targets
Gayan Balasooriya …
Understanding programmed cellular synthesis of resorbable scar after acute myocardial infarction
Philip Langer …
Our approach
Our targeted career development initiatives support REACT staff and students in becoming skilled, confident researchers who will shape the field of advanced cardiac therapies for decades to come. Through team science and collaboration, and by fostering an …
Greg Palmer
Greg leads patient and public involvement and engagement (PPIE) and digital communications efforts for the MRC/BHF CoRE in Advanced Cardiac Therapies (REACT). He is based at the University of Edinburgh but supports work across all our partner …
Culture and inclusion
Our unique position across three world-class institutions allows us to tap into distinct institutional strengths and practices in research culture – sharing, combining and amplifying them within REACT. To build and sustain a positive research culture we …
Dr Nicola Haines
As REACT COO Nicola works to ensure that we have the strategic and operational capacity to allow the science to run smoothly while maximising the opportunities to reach our goals and deliver impact on behalf of our funders, partners and publics. In REACT, …
Professor Daniel Stuckey
Daniel is Professor of Cardiovascular Imaging at University College London. For over 20 years his team have been developing in vivo imaging technology bespoke to cardiac regenerative therapies. Through successive BHF Fellowships, his team have established …