Professor Susan Rosser
Susan is Professor of Synthetic Biology at the University of Edinburgh, where she also directs the UKRI Engineering Biology for Advanced Therapeutics Hub and co-directs the Edinburgh Genome Foundry. A major challenge for gene therapies is that to be …
Dr Miguel Mano
Miguel Mano is Senior Lecturer and Head of the High-Throughput Screening Facility at King's College London. He has extensive expertise and a strong track-record in the implementation of high-throughput and high-content screenings using small compounds and …
Itamar Levin
Itamar is a REACT-funded PhD student with over three years of wet lab experience investigating RNA and RNA binding proteins. It has been demonstrated that following cardiac infarction that many RNAs within the cells undergo alternative splicing leading to …
Emma Jones
Emma is a REACT-funded DPhil student in the Department of Physiology, Anatomy and Genetics at the University of Oxford, supervised by Dr Ian McCracken. Her research investigates how new blood vessels form in the adult heart after a heart attack, and how …
Dr Andreas Gerondopoulos
Andreas is REACT's Programme Manager, working from King's College London to support work across the centre. Andreas has a background in vesicle trafficking, cell biology and rare disease which provides a strong foundation for understanding the molecular …
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Horace Chan
Horace Chan is a PhD student who recently started a REACT studentship under the supervision of Professors Mairi Brittan, Andy Baker and Dave Newby at the University of Edinburgh. Horace completed an MScR at the Institute for Regeneration and Repair at the …
Patient partnerships
Our work is destined to have a direct impact on people living with heart attack and heart failure, their carers and families. These people have valuable lived experience that can help shape our research questions, approach and engagement. We recognise the …
Lived experience advocates
Cardiovascular disease is the number one cause of death worldwide. Coronary artery disease leading to heart attack and ultimately heart failure is the biggest contributor. There is no known cure for heart failure, other than organ transplantation. This …
Determining mechanisms of cardiomyocyte proliferation-driven vascularisation
Although survival rates after myocardial infarction (MI) have improved, permanent loss of heart muscle cells often results in progressive heart failure. Restoring blood supply through angiogenesis (the growth of new blood vessels) could protect vulnerable …