Dr Ermes Carulli
Ermes is a cardiologist and biotechnologist with a special interest in interventional cardiology and advanced cardiac imaging. Ermes has a PhD in Translational Medicine and experience in early clinical trial design and delivery, having previously led a …
Screening for drivers of lymphangiogenesis
Christophe Ravaud …
Professor Dame Molly Stevens
Molly is the the John Black Professor of Bionanoscience at the University of Oxford, with joint appointments in the Departments of Physiology, Anatomy & Genetics and Engineering Science, and Deputy Director of the Kavli Institute for Nanoscience …
Target discovery
REACT members have pioneered the concept that small non-coding RNAs, mRNAs and cDNAs can be identified by screening and then administered to achieve cardiac regeneration. Therapeutic targets include stimulating cardiomyocyte proliferation, inducing the …
Using lipid nanoparticles to deliver small RNAs to the heart
Manendra Pachauri …
Dr Roman Fischer
Roman is an Associate Professor at the Target Discovery Institute and Centre for Medicines Discovery in the Nuffield Department of Medicine at the University of Oxford. Roman leads two proteomics-focussed laboratories: the Discovery Proteomics Facility …
Professor Ajay Shah
Ajay is BHF Chair of Cardiology and Executive Dean of the Faculty of Life Sciences & Medicine at King's College London, and an Honorary Consultant Cardiologist at King’s College Hospital. Ajay has a long-standing track record of innovative research in the …
Professor Mairi Brittan
Mairi is Professor of Cardiovascular Regeneration at the University of Edinburgh and co-investigator with REACT. Her area of expertise is using multimodal omics technology (single cell and nucleus RNA sequencing and spatial transcriptomics) to identify …
Dr Michael Weinberger
Michael started to work on heart development and repair when doing his PhD. Investigating the zebrafish, he characterised different cell populations in the epicardium, the outer cell layer of the heart. He went on to study the regulation of gene …
Dr Joaquim Nunes Vieira
Joaquim leads a research group at King’s College London focused on epicardial–vascular–stromal signalling in cardiac development and regeneration. His work uses preclinical and human models to study how the epicardium, the outer layer of the heart, …