Identifying early response RNA binding proteins in cardiac fibrosis
Giancarlo Forte …
Computationally identifying conserved drivers of cardiac repair
The injured heart undergoes coordinated phases of inflammation, proliferation and maturation, comprising interconnected biological processes that determine reparative capacity. These include regeneration of lost myocardium, recruitment and activation of …
Exploring long non-coding RNAs as therapeutic targets
Gayan Balasooriya …
Understanding programmed cellular synthesis of resorbable scar after acute myocardial infarction
Philip Langer …
Cardiac delivery
We aim to achieve cardiac-specific targeting of vectors and nanoparticle-delivered nucleic acid medicines to minimise adverse effects and allow for effective, inducible and/or regulated expression of single or multiple target therapeutic nucleic acids. …
Our research
We aim to discover and target fundamental processes that drive heart failure and regulate cardiac regeneration. Our therapeutic products will leverage endogenous reparative processes to generate new heart muscle, promote vessel formation and resolve …
Clinical translation
A comprehensive array of pre-clinical models will be utilised to test therapeutic leads generated by REACT. Existing targets will be fast tracked for safety and efficacy assessment in models of chronic heart failure conditions, and then prioritised for …
Jobs
Location: Oxford, UK (onsite) Salary: £35,681-£37,338 per annum Contract: 2 year fixed term, full-time Application deadline: Friday 10 April 2026, 12:00 noon Dr Tom Mulroney is recruiting a research assistant to work on a REACT-funded research project …
Studentships
Location: Edinburgh, UK (onsite) Funding: fully funded 4-year studentship Application deadline: Friday 17 April 2026 Dr Appie Beqqali is recruiting a PhD student to work on a project to understand molecular mechanisms that regulate regeneration in the …
Events
The REACT symposium is our annual meeting for members, collaborators, funders and guests across the broad network of the MRC/BHF CoRE in Advanced Cardiac Therapies. The first event took place in London in March 2026. More information about this and future …