AAV6-based ZEB2 delivery promotes cardiomyocyte dedifferentiation in adult human myocardium
Rocco Caliandro …
Environmental sustainability
Each of our three principal partner institutions has developed ambitious sustainability strategies, underpinned by substantial investment and a shared commitment to climate action. As signatories to the Race to Zero for Universities and Colleges , they …
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First annual symposium brings together growing REACT community
Members of the MRC/BHF CoRE in Advanced Cardiac Therapies (REACT) gathered in London last week for our first annual symposium. The meeting built on progress from our first year of operation and showcased the breadth of projects underway across the …
Clinical translation
A comprehensive array of pre-clinical models will be utilised to test therapeutic leads generated by REACT. Existing targets will be fast tracked for safety and efficacy assessment in models of chronic heart failure conditions, and then prioritised for …
Cardiac delivery
We aim to achieve cardiac-specific targeting of vectors and nanoparticle-delivered nucleic acid medicines to minimise adverse effects and allow for effective, inducible and/or regulated expression of single or multiple target therapeutic nucleic acids. …
Professor Andy Baker
Andy is BHF Professor of Translational Cardiovascular Sciences and Gustav Born Chair of Vascular Biology at the University of Edinburgh. He has a long standing interest in the understanding of vascular pathophysiology. Andy's laboratory was set up with …
Symposium
Annual events will allow our growing REACT community to gather, network and forge new collaborations. Our first symposium brought members together in person, in London, and online, in March …
Operations team
The REACT operations team manage the activities of the MRC/BHF CoRE in Advanced Cardiac Therapies on behalf of the leadership team . Led by Dr Nicola Haines , Chief Operating Officer, the team works closely with professional services colleagues at the …