Counteracting cardiac fibrosis through LNP-mediated microRNA delivery
Fibrosis underpins all forms of cardiac disease. Cardiac fibrosis ensues from an over-activation of cardiac fibroblasts upon cardiac injury and their differentiation into myofibroblasts. Fibroblast activation is initially of protective nature, but …
Our research
We aim to discover and target fundamental processes that drive heart failure and regulate cardiac regeneration. Our therapeutic products will leverage endogenous reparative processes to generate new heart muscle, promote vessel formation and resolve …
First human whole-body biodistribution and dosimetry analysis of [18F]LW223, a novel TSPO PET radiotracer
Phyo H. Khaing …
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis
Rupen Hargreaves …
Professor Thierry Pedrazzini
Thierry is Professor of Experimental Cardiology at King’s College London. He previously served as a faculty member at the University of Lausanne Medical School, Switzerland. His research aims to understand how the adult heart adapts to injury and stress, …
Dr Giancarlo Forte
Giancarlo brings expertise in mechanosensing and advanced in vitro disease models to REACT. His group has been working at the forefront of the field for more than a decade. They revealed how the mechanical stress associated with ECM remodelling in the …
Dr Maria Castillo Bohorquez
Maria is a postdoctoral research scientist in the group of Molly Stevens at the University of Oxford, designing innovative biomaterials and approaches for gene and drug …
Dr Sida Wang
Sida is a postdoctoral research scientist in the group of Molly Stevens at the University of Oxford, investigating innovative biomaterials for therapeutic …
Dr Peter Vegh
Peter is Biofoundry Computational Biology Lead at the Edinburgh Genome Foundry, University of Edinburgh. …
Dr Gayan Balasooriya
Gayan is a postdoctoral researcher at King's College London. …