Professor Mauro Giacca
Mauro is Professor of Cardiovascular Sciences and Head of the School of Cardiovascular and Metabolic Medicine & Sciences at King’s College London. His current research interests focus on the development of nucleic acid therapeutics (RNA, AAV vectors) for …
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Gene therapy in cardiac and vascular diseases: a review of approaches to treat genetic and common cardiovascular diseases with novel gene-based therapeutics
Patricia Musolino …
Gene Horizons
Cameron Duguid …
Developing a small molecule drug-controllable system in a clinical AAV vector for cardiac gene therapy
Adeno-associated virus (AAV) vectors typically deliver a genetic information under a promoter that is either ubiquitous or cell-specific, but with no other means of control. Controllable systems, which can be used to turn off or titrate gene expression or …
Professor Brian Bigger
Brian is an expert in translational gene therapy, having developed several lentiviral-based ex vivo haematopoietic stem cell gene therapies for childhood dementias and taken these through to Phase I/II clinical trial. He has also developed and worked …
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